A case of atypical hemolytic uremic syndrome as an early manifestation of acute lymphoblastic leukemia / 소아과
Korean Journal of Pediatrics
;
: 253-257, 2010.
Article
Dans Anglais
| WPRIM
| ID: wpr-125466
ABSTRACT
Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children younger than 4 years and is characterized by microangiopathic hemolytic anemia, acute renal failure, and thrombocytopenia. HUS associated with diarrheal prodrome is usually caused by Shiga toxin-producing Escherichia coli O157H7 or by Shigella dysenteriae, which generally has a better outcome. However, atypical cases show a tendency to relapse with a poorer prognosis. HUS has been reported to be associated with acute lymphoblastic leukemia (ALL) in children. The characteristics and the mechanisms underlying this condition are largely unknown. In this study, we describe the case of an 11-year-old boy in whom the diagnosis of ALL was preceded by the diagnosis of atypical HUS. Thus, patients with atypical HUS should be diagnosed for the possibility of developing ALL.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Récidive
/
Shigella dysenteriae
/
Thrombopénie
/
Escherichia coli producteur de Shiga-toxine
/
Leucémie-lymphome lymphoblastique à précurseurs B et T
/
Atteinte rénale aigüe
/
Syndrome hémolytique et urémique
/
Anémie hémolytique
Type d'étude:
Étude pronostique
Limites du sujet:
Enfant
/
Humains
langue:
Anglais
Texte intégral:
Korean Journal of Pediatrics
Année:
2010
Type:
Article
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