Proteomic applications of surface plasmon resonance biosensors: analysis of protein arrays
Experimental & Molecular Medicine
;
: 1-10, 2005.
Article
Dans Anglais
| WPRIM
| ID: wpr-128161
ABSTRACT
Proteomics is one of the most important issues in the post-genomic area, because it can greatly contribute to identifying protein biomarkers for disease diagnosis and drug screening. Protein array is a key technology for proteome researches and has been analyzed by various methods including fluorescence, mass spectrometry, atomic force microscopy and surface plasmon resonance (SPR). SPR biosensor is a promising technology in proteomics, since it has various advantages including real-time measurement of biomolecular interactions without labeling and the simple optical system for the device. SPR biosensors have a strong potential for analyzing proteomes by SPR imaging and SPR spectroscopic imaging, even though the challenge is to produce proteins on a proteomic scale.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Techniques de biocapteur
/
Résonance plasmonique de surface
/
Analyse par réseau de protéines
/
Protéomique
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Experimental & Molecular Medicine
Année:
2005
Type:
Article
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