Pneumatosis Intestinalis Developed due to CMV Infection in a Pediatric Severe Aplastic Anemia Patient after Hematopoietic Stem Cell Transplantation / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
;
: 112-115, 2013.
Article
Dans Coréen
| WPRIM
| ID: wpr-130758
ABSTRACT
A 10-year old girl diagnosed as severe aplastic anemia was transplanted with peripheral stem cells from a CMV seropositive full matched unrelated donor. The conditioning regimen consisted of busulfan, fludarabine, and anti-thymocyte globulin (ATG). At D+114, abdominal pain, fever, and blood-tinged watery diarrhea developed. At D+116, pneumatosis intestinalis (PI) was detected on simple abdominal X-ray and computed tomography (CT). Ganciclovir was started intravenously because CMV antigenemia was detected at D+117. Two days later, PI sign disappeared on simple abdominal X-ray, and hematochezia began to decrease. CMV antigenemia disappeared 10 days after starting ganciclovir. We describe a 10-year old girl with severe aplastic anemia who developed PI in the presence of CMV infection and gastro-intestinal graft-versus-host-disease (GVHD) after allogeneic stem cell transplantation and was treated successfully with ganciclovir.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Cellules souches
/
Vidarabine
/
Busulfan
/
Cellules souches hématopoïétiques
/
Douleur abdominale
/
Ganciclovir
/
Transplantation de cellules souches hématopoïétiques
/
Transplantation de cellules souches
/
Diarrhée
/
Fièvre
Limites du sujet:
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Clinical Pediatric Hematology-Oncology
Année:
2013
Type:
Article
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