Platelet to lymphocyte ratio as a prognostic factor for epithelial ovarian cancer / 부인종양
Journal of Gynecologic Oncology
;
: 265-273, 2012.
Article
Dans Anglais
| WPRIM
| ID: wpr-131051
ABSTRACT
OBJECTIVE:
To determine whether preoperative platelets to lymphocyte ratio (PLR) could predict disease stage, surgical outcome, and survival in patients with epithelial ovarian cancer (EOC).METHODS:
Medical records of EOC patients who had surgery between January 2004 and December 2010 were reviewed. Clinicopathological and complete blood count data were collected. The optimal predictive value of PLR to predict advanced stage, suboptimal surgery, and survival was determined and compared with those of thrombocytosis (> or =400,000 cells/mm3) and neutrophil to lymphocyte ratio (NLR) > or =2.6.RESULTS:
A total of 166 EOC patients were included in the study. PLR of 200 yielded better predictive values than those of thrombocytosis and NLR > or =2.6. The area under curve (AUC), sensitivity, specificity, positive and negative predictive values, and accuracy of PLR to predict advanced stage were 0.66, 59.0%, 72.7%, 65.7%, 66.7%, and 66.3%, respectively. The corresponding values to predict suboptimal surgery were 0.70, 70.0%, 69.8%, 50.0%, 84.4%, and 69.9%. The patients who had PLR> or =200 had significantly shorter progression-free and overall survivals than those with PLR2.6.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Tumeurs de l'ovaire
/
Thrombocytose
/
Hémogramme
/
Plaquettes
/
Lymphocytes
/
Dossiers médicaux
/
Sensibilité et spécificité
/
Tumeurs épithéliales épidermoïdes et glandulaires
/
Aire sous la courbe
/
Granulocytes neutrophiles
Type d'étude:
Etude diagnostique
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Journal of Gynecologic Oncology
Année:
2012
Type:
Article
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