Comparison of elective single cleavage-embryo transfer to elective single blastocyst-embryo transfer in human IVF-ET / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
;
: 53-60, 2011.
Article
Dans Anglais
| WPRIM
| ID: wpr-133467
ABSTRACT
OBJECTIVE:
This study was carried out to compare the clinical outcome of elective single cleavage-embryo transfer (eSCET) to that of elective single blastocyst-embryo transfer (eSBET) in human IVF-ET.METHODS:
This study was a retrospective study which analyzed for 614 women who visited the Daegu Maria Clinic from August 2008 to December 2009. All were under 37 years old and had more than 8 mm of endometrial thickness on the day of hCG administration and at least one good quality embryo on day 3. The eSCETs were performed on day 3 (n=450) and the eSBETs were conducted on day 5 (n=164).RESULTS:
The numbers of retrieved oocytes, fertilized oocytes, and day 3 good quality embryos were significantly lower in the eSCET group (12.1+/-6.0, 8.2+/-4.6, and 4.2+/-3.1, respectively) compared to the eSBET group (16.7+/-7.2, 12.1+/-5.0, and 8.5+/-4.5, respectively; p<0.001). However, the clinical pregnancy, implantation, on-going pregnancy, and live birth rates of the eSCET group (46.7, 46.9, 40.0, and 36.7%, respectively) were not statistically different from those of the eSBET group (51.2, 51.8, 45.1, and 43.9%, respectively; p=0.318, 0.278, 0.254, and 0.103, respectively).CONCLUSION:
These results suggested that elective single embryo transfer should be performed regardless of the developmental stage to women less than 37 years old who had more than 8 mm of endometrial thickness on the hCG administration day and at least one good quality embryo on day 3 in order to reduce the twin pregnancy rate without reducing the whole pregnancy rate.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Ovocytes
/
Jumeaux
/
Études rétrospectives
/
Taux de grossesse
/
Structures de l'embryon
/
Naissance vivante
/
Transfert d'embryon unique
/
Grossesse gémellaire
Type d'étude:
Étude observationnelle
Limites du sujet:
Femelle
/
Humains
/
Grossesse
langue:
Anglais
Texte intégral:
Clinical and Experimental Reproductive Medicine
Année:
2011
Type:
Article
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