Increased survival in hepatitis c patients who underwent living donor liver transplant: a case-control study with propensity score matching
Annals of Surgical Treatment and Research
;
: 293-299, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-134100
ABSTRACT
PURPOSE:
There is no consensus regarding the difference in outcomes of HCV in patients who receive living donor liver transplantation (LDLT) or compared to deceased donor liver transplantation (DDLT). The aims of this study were to compare characteristics between LDLT and DDLT groups and to identify risk factors affecting patient survival.METHODS:
We retrospectively reviewed the multicenter records of 192 HCV RNA-positive patients who underwent liver transplantation.RESULTS:
Thirty-five patients underwent DDLT, and 146 underwent LDLT. The 1-, 3-, and 5-year patient survival rates were 66.7%, 63.0%, and 63.0% in the DDLT group and 86.1%, 82.3%, and 79.5% in the LDLT group (P = 0.024), respectively. After propensity matching, the patient survival curve of the LDLT group was higher than that of the DDLT group. However, there was no statistically significant difference in patient survival between the 2 groups (P = 0.061). Recipient age ≥ 60 years, LDLT, and use of tacrolimus were positively associated with patient survival in multivariate analyses.CONCLUSION:
LDLT appears to be suitable for HCV-infected patients if appropriate living donor is available.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Donneurs de tissus
/
Études cas-témoins
/
Analyse multifactorielle
/
Taux de survie
/
Études rétrospectives
/
Facteurs de risque
/
Immunosuppression thérapeutique
/
Transplantation hépatique
/
Tacrolimus
/
Hépatite C
Type d'étude:
Etude d'étiologie
/
Guide de pratique
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Annals of Surgical Treatment and Research
Année:
2017
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS