Stereotactic Body Radiotherapy for Isolated Para-aortic Lymph Node Recurrence after Curative Resection in Gastric Cancer
Journal of Korean Medical Science
; : 488-492, 2009.
Article
de En
| WPRIM
| ID: wpr-134343
Bibliothèque responsable:
WPRO
ABSTRACT
The aim of this study was to investigate whether stereotactic body radiotherapy (SBRT) can salvage gastric cancer patients with para-aortic lymph node (PALN) recurrence. From January 2003 to December 2006, 7 patients were treated for isolated PALN recurrence from gastric cancer after curative resection. Follow up durations ranged from 19 to 33 months (median; 26 months), and SBRT doses from 45 Gy to 51 Gy (median 48 Gy) in 3 fractions. Disease progression-free and overall survivals and toxicities were recorded. Response to treatment was assessed by computed tomography. Final patient outcomes were as follows: 2 were alive without evidence of disease, 3 remained alive with disease, and 2 patients died of disease. Five of 7 patients showed complete response and 2 patients partial response between 3 and 11 months after SBRT. Three-year overall and disease progression-free survival rates post-SBRT were 43% and 29%, respectively. No severe complication was detected during follow-up. Selected patients with isolated PALN recurrence can be salvaged by SBRT without severe complications.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Dosimétrie en radiothérapie
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Récidive
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Tumeurs de l'estomac
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Analyse de survie
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Radiochirurgie
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Survie sans rechute
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Noeuds lymphatiques
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Métastase lymphatique
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Récidive tumorale locale
Limites du sujet:
Adult
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Aged
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Female
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Humans
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Male
langue:
En
Texte intégral:
Journal of Korean Medical Science
Année:
2009
Type:
Article