Epstein-Barr Virus Brainstem Encephalitis With Anti-N-methyl-D-aspartate Receptor Antibodies
Journal of the Korean Neurological Association
; : 199-202, 2013.
Article
de Ko
| WPRIM
| ID: wpr-135474
Bibliothèque responsable:
WPRO
ABSTRACT
The neurological manifestations caused by Epstein-Barr virus (EBV) occur only rarely in association with its primary infection or reactivation. The mechanism by which EBV produces neurological disease is unknown. This article describes two cases of polymerase-chain-reaction-proven EBV brainstem encephalitis. The sera of both patients contained autoantibodies against N-methyl-D-aspartate receptor (NMDAR), suggesting the presence of a secondary immunological mechanism. Prospective studies are needed to reveal whether the subgroup of patients with EBV encephalitis and anti-NMDAR antibodies have different clinical presentations and would benefit from immunotherapy.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Autoanticorps
/
Tronc cérébral
/
N-Méthyl-aspartate
/
Herpèsvirus humain de type 4
/
Encéphalite
/
Immunothérapie
/
Anticorps
/
Manifestations neurologiques
Type d'étude:
Observational_studies
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Journal of the Korean Neurological Association
Année:
2013
Type:
Article