Phenotypic Differences of Gastric Cancer according to the Helicobacter pylori Infection in Korean Patients
Journal of Gastric Cancer
;
: 168-174, 2010.
Article
Dans Anglais
| WPRIM
| ID: wpr-139728
ABSTRACT
PURPOSE:
Infection with Helicobacter pylori is an important risk factor for gastric cancer in humans. We compared the clinicopathologic features of gastric cancer patients based on H. pylori infection. MATERIALS ANDMETHODS:
We prospectively studied 155 patients who had gastric cancer and underwent gastrectomies in 1 hospital in Korea. We examined H. pylori infections using the rapid urease test (RUT) with gastrectomy specimens and collected clinical and pathologic data.RESULTS:
The number of H. pylori infections based on the RUT was 137 (88%). The H. pylori-negative group was significantly associated with AGC and tumor histology. H. pylori infection was significantly correlated with type I/IIa in EGC and type III/IV/V in AGC. AGC was significantly correlated with larger tumor size, lymphatic invasion, perineural invasion, and H. pylori infection based on univariate and multivariate analyses.CONCLUSIONS:
We report the prevalence of H. pylori based on the RUT in gastric cancer patients. H. pylori infection influences the tumor histology, progression, and growth type of gastric cancer.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Phénotype
/
Tumeurs de l'estomac
/
Urease
/
Prévalence
/
Études prospectives
/
Facteurs de risque
/
Helicobacter pylori
/
Helicobacter
/
Gastrectomie
/
Corée
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Journal of Gastric Cancer
Année:
2010
Type:
Article
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