The Molecular Pathogenesis of Pituitary Adenomas: An Update
Endocrinology and Metabolism
; : 245-254, 2013.
Article
de En
| WPRIM
| ID: wpr-141197
Bibliothèque responsable:
WPRO
ABSTRACT
Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adenomas. Although the pathogenesis of pituitary adenomas is largely unknown, considerable evidence indicates that the pituitary tumorigenesis is a complex process involving multiple factors, including genetic and epigenetic changes. This review summarized the recent progress in the study of pituitary tumorigenesis, focusing on the role of tumor suppressor genes, oncogenes and microRNAs.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Oncogènes
/
Hormones hypophysaires
/
Tumeurs de l'hypophyse
/
Tumeurs du cerveau
/
Cycle cellulaire
/
Transformation cellulaire néoplasique
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Gènes suppresseurs de tumeur
/
MicroARN
/
Épigénomique
Type d'étude:
Etiology_studies
langue:
En
Texte intégral:
Endocrinology and Metabolism
Année:
2013
Type:
Article