Diagnosis and Treatment of Gastrointestinal Stromal Tumor / 대한내과학회지
Korean Journal of Medicine
;
: 341-353, 2013.
Article
Dans Coréen
| WPRIM
| ID: wpr-142789
ABSTRACT
Gastrointestinal stromal tumors (GISTs), which are the most common mesenchymal tumors of the gastrointestinal tract, have represented an important advance in oncology field with the success of molecular targeted therapy. Since the approval of the tyrosine kinase inhibitor (imatinib) in 2002, the survival of patients with advanced GISTs has significantly increased. Accurate histopathologic diagnosis of GISTs and multidisciplinary approach has become more important for successful management of GISTs. Recently, imatinib has become a standard treatment even in adjuvant setting, and regorafenib has been approved for advanced GIST after failure of imatinib and sunitinib. This review presents here the updated results of relevant clinical studies for the further revision to the guideline of Korean GIST study group. We hope this review will help enhance the quality of diagnosis, treatment, and care of patients with GIST in Korea.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Phénylurées
/
Pipérazines
/
Pyridines
/
Pyrimidines
/
Pyrroles
/
Benzamides
/
Protein-tyrosine kinases
/
Tube digestif
/
Tumeurs stromales gastro-intestinales
/
Thérapie moléculaire ciblée
Type d'étude:
Etude diagnostique
/
Guide de pratique
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Korean Journal of Medicine
Année:
2013
Type:
Article
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