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Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction
Journal of Korean Medical Science ; : 1456-1461, 2010.
Article Dans Anglais | WPRIM | ID: wpr-14310
ABSTRACT
We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute ST-elevation myocardial infarction (STEMI) between November 2005 and December 2006 were categorized according to the National Cholesterol Education Program-Adult Treatment Panel III criteria of MS. Primary study outcomes included major adverse cardiac events (MACE) during one-year follow-up. Patients were grouped based on existence of MS group I MS (n=1,182, 777 men, 62.8+/-12.3 yr); group II Non-MS (n=808, 675 men, 64.2+/-13.1 yr). Group I showed lower left ventricular ejection fraction (LVEF) (P=0.005). There were no differences between two groups in the coronary angiographic findings except for multivessel involvement (P=0.01). The incidence of in-hospital death was higher in group I than in group II (P=0.047), but the rates of composite MACE during one-year clinical follow-up showed no significant differences. Multivariate analysis showed that low LVEF, old age, MS, low high density lipoprotein cholesterol and multivessel involvement were associated with high in-hospital death rate. In conclusion, MS is an important predictor for in-hospital death in patients with STEMI.
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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pronostic / Protéine C-réactive / Maladie aigüe / Analyse multifactorielle / Valeur prédictive des tests / Facteurs âges / Résultat thérapeutique / Coronarographie / Dysfonction ventriculaire gauche / Syndrome métabolique X Type d'étude: Étude pronostique Limites du sujet: Adulte très âgé / Femelle / Humains / Mâle langue: Anglais Texte intégral: Journal of Korean Medical Science Année: 2010 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pronostic / Protéine C-réactive / Maladie aigüe / Analyse multifactorielle / Valeur prédictive des tests / Facteurs âges / Résultat thérapeutique / Coronarographie / Dysfonction ventriculaire gauche / Syndrome métabolique X Type d'étude: Étude pronostique Limites du sujet: Adulte très âgé / Femelle / Humains / Mâle langue: Anglais Texte intégral: Journal of Korean Medical Science Année: 2010 Type: Article