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Effects of a Novel Push-through Technique Using the Implantable Collamer Lens Injector System for Graft Delivery during Endothelial Keratoplasty
Korean Journal of Ophthalmology ; : 87-92, 2013.
Article Dans Anglais | WPRIM | ID: wpr-143913
ABSTRACT

PURPOSE:

To investigate effects of a new push-through insertion method for donor lenticules using an injector system on endothelial viability ex vivo and in a clinical case series of endothelial keratoplasty.

METHODS:

An ex vivo delivery model was used with porcine corneoscleral rims. We compared the endothelial viability in a new push-through insertion method using the Visian Implantable Collamer Lens (ICL) injector versus that of standard forceps-assisted insertion for lenticule delivery. Twenty porcine corneal lenticules were divided into four groups by insertion method and wound size. Vital dye staining was performed and devitalized areas were semi-quantitatively assessed by digital imaging. In the clinical case series, Descemet's stripping endothelial keratoplasty (DSEK) using the push-through method was performed in seven patients and endothelial outcome was determined six months postoperatively.

RESULTS:

Mean devitalized areas for the push-through method were significantly lower than for forceps-assisted insertion through 3.2 mm incision (23.99 +/- 2.17% vs. 50.48 +/- 5.07%, p = 0.009) in the ex vivo model. Average endothelial cell counts of donor tissues of patients who underwent DSEK were 26.4% lower six months postoperatively.

CONCLUSIONS:

Push-through delivery of donor lenticules using the Visian ICL injector system appears to be less harmful to endothelial cells than conventional forceps-assisted delivery.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Complications postopératoires / Conception de prothèse / Suidae / Pose d'implant intraoculaire / Modèles animaux / Perte de cellules endothéliales cornéennes / Kératoplastie endothéliale automatisée par le stripping de Descemet / Lentilles intraoculaires Limites du sujet: Animaux langue: Anglais Texte intégral: Korean Journal of Ophthalmology Année: 2013 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Complications postopératoires / Conception de prothèse / Suidae / Pose d'implant intraoculaire / Modèles animaux / Perte de cellules endothéliales cornéennes / Kératoplastie endothéliale automatisée par le stripping de Descemet / Lentilles intraoculaires Limites du sujet: Animaux langue: Anglais Texte intégral: Korean Journal of Ophthalmology Année: 2013 Type: Article