Effectiveness of Preoperative Intravitreal Bevacizumab Injections in Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy
Journal of the Korean Ophthalmological Society
;
: 1221-1225, 2009.
Article
Dans Coréen
| WPRIM
| ID: wpr-144219
ABSTRACT
PURPOSE:
To evaluate the efficacy of preoperative intravitreal bevacizumab (Avastin(R); Genetech, San Francisco, CA, USA) injections of pars plana vitrectomy (PPV) for proliferative diabetic retinopathy (PDR).METHODS:
Thirty patients (30 eyes) who underwent PPV for treatment of PDR and received a preoperative intravitreal bevacizumab injection of 1.25 mg were retrospectively analyzed. The study group (group 1, 30 patients, 30 eyes) was compared with a control group (group 2, 29 patients, 30 eyes and matched with the study group for preoperative parameters) who underwent PPV without preoperative intravitreal bevacizumab injection.RESULTS:
In both groups, visual acuity improved but there was no statistical significance. Intraoperative vitreous hemorrhage occurred in 14 eyes (46.7%) from group 1 and 11 eyes (36.7%) from group 2. There was no statistical significance of intraoperative bleeding occurrence (p=0.3). Postoperative vitreous hemorrhage occurred in 4 eyes from group 1 and 14 eyes from group 2. The group 1 had a lower incidence of postoperative hemorrhage than group 2 (p=0.005).CONCLUSIONS:
Preoperative intravitreal bevacizumab injection appears effective in decreasing early postoperative vitreous hemorrhage and maybe technically helpful in PPV for PDR.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Vitrectomie
/
Hémorragie du vitré
/
Acuité visuelle
/
Incidence
/
Études rétrospectives
/
San Francisco
/
Hémorragie postopératoire
/
Rétinopathie diabétique
/
Oeil
/
Anticorps monoclonaux humanisés
Type d'étude:
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
Pays comme sujet:
Amérique du Nord
langue:
Coréen
Texte intégral:
Journal of the Korean Ophthalmological Society
Année:
2009
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS