Evaluation of Donor Corneal Endothelium after Keratoplasty
Journal of the Korean Ophthalmological Society
;
: 519-524, 2006.
Article
Dans Coréen
| WPRIM
| ID: wpr-144251
ABSTRACT
PURPOSE:
To investigate the difference in donor corneal cell changes after penetrating keratoplasty in various corneal diseases.METHODS:
Subjects included 36 eyes from 35 people with at least 6 months of follow-up who had undergone penetrating keratoplasty between August 2000 and December 2002. The patients were classified into three groups based on the state of the corneal endothelium. Changes in cell density, polymorphisms, and polymegathism of the donor cornea were compared between groups. Results were analyzed by ANOVA.RESULTS:
The overall corneal endothelial cell density after grafting was lower, but the differences in endothelial cell states between the recipient cases were not statistically significant. The change in corneal endothelial cell density showed a significantly higher difference (p=0.0013) when patients had either undergone a rejection episode during recovery or recurred herpetic uveitis.CONCLUSIONS:
The preoperative state of the corneal endothelium may affect the survival of donor corneal endothelium after grafting. However, rejection of the transplant contributes more significantly to the survival of the donor corneal endothelium than other factors. We suggest close observation and keen therapy with respect to rejection after grafting.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Donneurs de tissus
/
Uvéite
/
Endothélium de la cornée
/
Numération cellulaire
/
Études de suivi
/
Transplantation de cornée
/
Kératoplastie transfixiante
/
Cornée
/
Maladies de la cornée
/
Transplants
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Ophthalmological Society
Année:
2006
Type:
Article
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