Your browser doesn't support javascript.
loading
Increased Risk of Asymptomatic Gallstones in Patients With Ulcerative Colitis
Intestinal Research ; : 122-127, 2015.
Article Dans Anglais | WPRIM | ID: wpr-144352
ABSTRACT
BACKGROUND/

AIMS:

The relationship between Crohn's disease and gallstones is established. However, the prevalence and risk factors for gallstones in patients with ulcerative colitis (UC) are not yet well understood. The aim of this study was to evaluate the prevalence and risk factors of gallstones in patients with UC.

METHODS:

This study was a retrospective single center study. A total of 87 patients with UC and 261 healthy controls were enrolled. Age, sex, and body mass index were matched. To investigate risk factors, the extent of UC, duration of disease, number of hospital admissions, and number of steroid treatments in patients with UC were evaluated.

RESULTS:

The prevalence of gallstones in patients with UC was 13.8%, whereas that in healthy controls was only 3.1% (P or =50 years of age had a 3.6-times higher risk of gallstones compared to that in those <50 years of age, and the difference was statistically significant (odds ratio, 3.60; confidence interval, 1.03-12.61) in univariate analysis. There were no statistically significant disease-related risk factors for gallstones in UC patients.

CONCLUSIONS:

This is the first study of gallstone prevalence in Korean UC patients. In this study, patients with UC had a higher prevalence of gallstones compared to that in well-matched healthy controls. Age seemed to be a possible risk factor, and more studies are needed. Further prospective, large-scale studies will be required to confirm the risk factors for gallstones in UC patients.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Rectocolite hémorragique / Maladie de Crohn / Calculs biliaires / Indice de masse corporelle / Prévalence / Études rétrospectives / Facteurs de risque / Maladies asymptomatiques Type d'étude: Etude d'étiologie / Étude observationnelle / Étude de prévalence / Facteurs de risque Limites du sujet: Humains langue: Anglais Texte intégral: Intestinal Research Année: 2015 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Rectocolite hémorragique / Maladie de Crohn / Calculs biliaires / Indice de masse corporelle / Prévalence / Études rétrospectives / Facteurs de risque / Maladies asymptomatiques Type d'étude: Etude d'étiologie / Étude observationnelle / Étude de prévalence / Facteurs de risque Limites du sujet: Humains langue: Anglais Texte intégral: Intestinal Research Année: 2015 Type: Article