Effect of Sodium Bicarbonate or Lidocaine Mixed with Rocuronium on Withdrawal Movement during Rocuronium Injection / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 160-163, 2004.
Article
Dans Coréen
| WPRIM
| ID: wpr-146191
ABSTRACT
BACKGROUND:
We have often observed arm withdrawal on administering rocuronium. This study was performed to determine the cause and to prevent this movement by mixing rocuronium with lidocaine or sodium bicarbonate.METHODS:
Sixty-two patients, ASA I-II, were randomized into three groups for this blind, prospective study. After induction of anesthesia by thiopental sodium 0.5 mg/kg, each group received rocuronium 0.6 mg/kg alone (group R), with 2% (2 ml) lidocaine (group L), or rocuronium with an equivalent volume of 8.4% sodium bicarbonate (group S). Patients' responses to the injection were graded using a 4-point scale and the pHs of the mixtures were measured.RESULTS:
The incidence rate of arm withdrawal was more reduced in groups L (47%) and S (45%) than in group R (80%) (P < 0.05). Severe withdrawal movement (grade 3) did not occur in group S (0%).CONCLUSIONS:
The incidence and the degree of withdrawal movement in response to the injection of rocuronium were significantly reduced by mixing an equivalent volume of 8.4% sodium bicarbonate with rocuronium.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Bras
/
Sodium
/
Thiopental
/
Incidence
/
Études prospectives
/
Hydrogénocarbonate de sodium
/
Concentration en ions d'hydrogène
/
Anesthésie
/
Lidocaïne
Type d'étude:
Essai clinique contrôlé
/
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Anesthesiology
Année:
2004
Type:
Article
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