Clinical Effects of Newfactan in the Treatment of Moderate to Severe Respiratory Distress Syndrome
Journal of the Korean Society of Neonatology
;
: 65-71, 2001.
Article
Dans Coréen
| WPRIM
| ID: wpr-146427
ABSTRACT
PURPOSE:
This study was designed to investigate the clinical effects of Newfactan in the treatment of moderate to severe respiratory distress syndrome.METHODS:
There were enrolled 20 preterm infants who were diagnosed as grade III or grade IV respiratory distress syndrome at Kosin University Gospel Hospital from July 1997 to May 2000. All of these preterm infants were treated for rescue. To investigate the improvement of respiratory parameters we used FiO2, MAP, a/APO2 ratio, OI.RESULTS:
Newfactan was administered to the patients at 7.2+/-7.4 hours (range 1.5- 32) after birth and 7 cases (35%) were administered one dose, 8 (40%) were administered two doses and 5 (25%) were administered three doses. The dose interval from first to second dose was 9.2+/-12.3 hours (range 5-46). The dose interval from second to third dose was 27.6+/-5.4 hours (range 21-35). The need of FiO2 showed decreased tendency especially between 4 to 6 hour after administration (P0.05). There were 41 complications and outcomes including PDA, sepsis, pneumothorax, intraventricular hemorrhage, BPD, ROP, and necrotizing enterocolitis.CONCLUSION:
The clinical effects of Newfactan in the treatment of grade III or grade IV respiratory distress syndrome were significant in improving FiO2, PaCO2, a/APO2 ratio and OI.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pneumothorax
/
Prématuré
/
Sepsie
/
Entérocolite nécrosante
/
Parturition
/
Hémorragie
Limites du sujet:
Humains
/
Nouveau-né
langue:
Coréen
Texte intégral:
Journal of the Korean Society of Neonatology
Année:
2001
Type:
Article
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