A Case of Hypersensitivity Pneumonitis Caused by Methotrexate / 결핵
Tuberculosis and Respiratory Diseases
;
: 203-209, 2004.
Article
Dans Coréen
| WPRIM
| ID: wpr-148835
ABSTRACT
BACKGROUND:
Methotrexate (MTX) has been used to treat a wide range of malignant and benign diseases including osteosarcoma, advanced stage non-Hodgkin's lymphoma, psoriasis, severe rheumatoid arthritis, sarcoidosis, and Wegener's granulomatosis. MTX-induced lung injury occurs in up to 10% of treated patients. Although both acute and chronic presentations have been described, typical manifestation of MTX-induced lung injury is subacute with symptoms usually developing within several months after starting therapy. Nonspecific interstitial pneumonia (NSIP) is the most common histopathologic manifestation of MTX-induced lung disease, while bronchiolitis obliterans organizing pneumonia (BOOP) and diffuse alveolar damage (DAD) are less common. Granuloma formation is reported in 34.7%. In Korea, Two reports of MTX pneumonitis have been published. The one presented with NSIP and the other with DAD. We recently experienced a case of MTX pneumonitis with presentation of hypersensitivity pneumonitis.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pneumopathie infectieuse
/
Polyarthrite rhumatoïde
/
Psoriasis
/
Sarcoïdose
/
Lymphome malin non hodgkinien
/
Ostéosarcome
/
Granulomatose avec polyangéite
/
Méthotrexate
/
Pneumopathies interstitielles
/
Pneumonie organisée cryptogénique
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Tuberculosis and Respiratory Diseases
Année:
2004
Type:
Article
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