Inflammatory Myofibroblastic Tumor of the Breast

ABSTRACT

Inflammatory myofibroblastic tumor (IMT) is an uncommon tumor which is composed of spindle cells admixed with mature plasma cells and inflammatory cells. IMT is most common in the lungs and in various organs. However, it is very rare in the breast. According to the organ, there are many clinical and histological characteristics. Breast IMT usually shows developed, movable nontender mass. Radiological findings of IMT are similar to primary breast malignancy. For accurate diagnosis, histologic correlation is needed. IMT is a benign lesion and excision is the treatment of choice, but wide local excision and negative resection margin is needed due to its tendency for recurrence. Understanding of the entity and its mimicry can be helpful in avoiding any unnecessary surgical procedures, such as mastectomy with or without lymph node dissection. Herein, the case of a 29-year-old woman found to have IMT of the breast. The patient underwent a wide local excision. The gross, microscopic and immunohistochemical findings were consistent with the diagnosis of IMT of the breast.