Clinical and cytogenetic analysis of midtrimester amniocentesis / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 365-373, 2006.
Article
Dans Coréen
| WPRIM
| ID: wpr-150836
ABSTRACT
OBJECTIVE:
To analyze clinical data based on prenatal genetic amniocentesis.METHODS:
We analyzed retrospectively maternal age, gestational age, indications, cytogenetic results and complications, based on a total of 496 cases of midtrimester prenatal genetic amniocentesis performed at Sungkyunkwan University School of Medicine, Kangbuk Samsung hospital from March 2000 to May 2005.RESULTS:
The most common age of total subjects was between 35-39 years (37.1%). The indications of amniocentesis were abnormal maternal serum marker (39.72%), advanced maternal age (35.89%), abnormal ultrasonographic finding (5.04%), combined old age and abnormal maternal serum marker (4.23%), in order. Since 2000, the number of amniocentesis due to abnormal ultrasonographic finding was increased. The overall incidence of chromosomal abnormalities were 6.05% (30/496). There was no significant difference between maternal age and abnormal fetal karyotype. According to indications, there was 7.11% (14/197) of chromosomal abnormalities in abnormal maternal serum screening group, 1.69% (3/178) in advanced maternal age group and 22.22% (6/27) in abnormal ultrasonographic finding group.CONCLUSION:
Abnormal maternal serum marker and advanced maternal age were the most common indication. There were frequent chromosomal abnormalities in combined old age and abnormal maternal serum marker group and abnormal ultrasonographic finding group.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Deuxième trimestre de grossesse
/
Marqueurs biologiques
/
Dépistage de masse
/
Incidence
/
Études rétrospectives
/
Aberrations des chromosomes
/
Âge gestationnel
/
Âge maternel
/
Analyse cytogénétique
/
Cytogénétique
Type d'étude:
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
/
Étude de dépistage
Limites du sujet:
Femelle
/
Humains
/
Grossesse
langue:
Coréen
Texte intégral:
Korean Journal of Obstetrics and Gynecology
Année:
2006
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS