A study of the current(2003-2005) prevalence of anti-HBs and immunologic memory of hepatitis B vaccine in children from the central area of Korea / 소아과
Korean Journal of Pediatrics
;
: 630-634, 2006.
Article
Dans Coréen
| WPRIM
| ID: wpr-151857
ABSTRACT
PURPOSE:
This study was conducted to assess the current(2003-2005) prevalence of anti-HBs and immunologic memory for Hepatitis B vaccine in children from the central area of Korea.METHODS:
Subjects were chosen from children and adolescents who received tests for hepatitis B surface antigen(HBsAg) and anti-HBs at Dankook University Hospital from March 2003 to May 2005. Among these, antibodies to hepatitis B core antigen(IgG anti-HBc) were checked. A single booster vaccination was performed on children whose anti-HBs titers were under 10 mIU/mL. One month after booster vaccination we rechecked the anti-HBs titer.RESULTS:
A total of 3,277 subjects were tested for HBsAg/anti-HBs, and 1,913(58.4 percent) of them were positive for anti-HBs. Of these, 29 subjects(0.9 percent) were positive for HBsAg. Positive results for anti-HBs by age were 78.6 percent for 6-12 months of age, 62.7 percent for 1-3 years of age, 51.9 percent for 4-6 years of age, 49.5 percent for 7-12 years of age, 63.4 percent for 13-15 years of age and 72.2 percent for 16-18 years of age. The 80 subjects who were tested negative for HBsAg/anti-HBs received a single booster vaccine, 71 subjects were tested positive for antibodies. IgG anti-HBc titer was checked for 169 of the subjects, 5 subjects were positive.CONCLUSION:
In our study, a significant anamnestic response was observed in 88.8 percent of children. This is believed to be a result of the relatively long immunologic memory effect of the hepatitis B vaccination in children from the central area of Korea.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Immunoglobuline G
/
Prévalence
/
Vaccination
/
Vaccins anti-hépatite B
/
Hépatite
/
Hépatite B
/
Antigènes de surface du virus de l'hépatite B
/
Mémoire immunologique
/
Corée
/
Anticorps
Type d'étude:
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Enfant
/
Humains
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Korean Journal of Pediatrics
Année:
2006
Type:
Article
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