Gastric Mucormycosis in a Renal Transplant Recipient / 대한소화기내시경학회지

ABSTRACT

Mucormycosis is a rare opportunistic infection caused by fungi of the nrder Mucorales. It occurs almost exclusively in immunocompromised patients, and the prognosis is grave. Rhinocerebral and pulmonary diseases are the most comrnon forms. Gastric mucormycosis is very rare and the manifestations range from colonization of peptic ulcers to infiltrative disease with vascular invasion and dissemination. Only one case of gastric mucormycosis was reported in Korean literature. We recently experienced a case of gastric mucormycosis in a renal transplant recipient. The 29-year-old male patient received a renal transplant from his rnother seven years ago, and had been on immunosuppressive therapy. He experienced intermittent epigastric pain for one week, and a gastroscopy revealed a huge gastric ulcer covered with black necrotic material. The diagnosis of gastric mucormycosis was confirmed on a histologic examination, and amphctericin B was administered. Despite two weeks of intensive medical therapy he expired due to shock and multiorgan failure. This is the first case of gastric mucormycosis in an organ transplant recipient in Koren.