The First Korean Case of Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium abscessus Subspecies bolletii in a Patient with Bronchiectasis / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 30-33, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-15356
ABSTRACT
We report the first Korean case of lung diseases caused by Mycobacterium abscessus subsp. bolletii in a previously healthy male, except for a previous history of pulmonary tuberculosis and bronchiectasis. All serial isolates are identified as M. abscessus subsp. bolletii by multi-locus sequence analysis based on the hsp65, rpoB, and 16S rRNA fragments. At the genetic level, the isolate has the erm(41) gene with a T28 sequevar, associated with clarithromycin resistance, and no rrl mutation. The isolate is resistant to clarithromycin. Although the symptoms and radiographic findings have improved after combination of antibiotics, the follow-up sputum cultures are persistently positive.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Expectoration
/
Tuberculose pulmonaire
/
Dilatation des bronches
/
Études de suivi
/
Analyse de séquence d'ADN
/
Analyse de séquence
/
Clarithromycine
/
Poumon
/
Maladies pulmonaires
/
Antibactériens
Type d'étude:
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Tuberculosis and Respiratory Diseases
Année:
2014
Type:
Article
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