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Endoscopic and Clinical Factors Affecting the Prognosis of Colorectal Endoscopic Submucosal Dissection-Related Perforation
Gut and Liver ; : 420-428, 2016.
Article Dans Anglais | WPRIM | ID: wpr-155140
ABSTRACT
BACKGROUND/

AIMS:

Although colorectal endoscopic submucosal dissection (ESD)-related perforation is not uncommon, the factors affecting clinical outcomes after perforation have not been investigated. This study was designed to investigate the factors influencing the clinical course of ESD-related colon perforation.

METHODS:

Forty-three patients with colorectal ESD-related perforation were evaluated. The perforations were classified as endoscopic or radiologic perforations. The patients' medical records and endoscopic pictures were analyzed.

RESULTS:

The clinical outcomes were assessed by the duration of nil per os, intravenous antibiotics administration, and hospital stays, which were 2.7±1.5, 4.9±2.3, and 5.1±2.3 days, respectively. Multivariate analyses revealed that a larger tumor size, ESD failure, specific endoscopists, and abdominal pain were independently related to a poorer outcome. The time between perforation and clipping was 15.8±25.4 minutes in the endoscopic perforation group. The multivariate analysis of this group indicated that delayed clipping, specific endoscopists, and abdominal pain were independently associated with poorer outcomes.

CONCLUSIONS:

Tumor size, ESD failure, abdominal pain, and the endoscopist were factors that affected the clinical outcomes of patients with colorectal ESD-related perforation. The time between the perforation and clipping was an additional factor influencing the clinical course of endoscopic perforation. Decreasing this time period may improve outcomes.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pronostic / Douleur abdominale / Dossiers médicaux / Analyse multifactorielle / Côlon / Durée du séjour / Antibactériens Type d'étude: Étude pronostique Limites du sujet: Humains langue: Anglais Texte intégral: Gut and Liver Année: 2016 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pronostic / Douleur abdominale / Dossiers médicaux / Analyse multifactorielle / Côlon / Durée du séjour / Antibactériens Type d'étude: Étude pronostique Limites du sujet: Humains langue: Anglais Texte intégral: Gut and Liver Année: 2016 Type: Article