Limitations of 99mTc-DMSA scan in diagnosing acute pyelonephritis in children / 소아과
Korean Journal of Pediatrics
;
: 408-413, 2010.
Article
Dans Coréen
| WPRIM
| ID: wpr-155214
ABSTRACT
PURPOSE:
We aimed to prove the relative limitation of 99mTc-DMSA scintigraphy (DMSA) compared to computed tomography (CT) in diagnosing acute pyelonephritis (APN) in children.METHODS:
Since September 2006, after a 64-channel CT was imported, 10 DMSA false-negative patients have been identified these patients underwent a CT scan for acute abdomen or acute febrile symptoms and were diagnosed as having APN; however, their DMSA scans were clear. We focused on these 10 DMSA false-negative patients and analyzed their clinical findings and CT results. We used Philips Brilliance Power 64-channel CT scanner for the CT scan and Siemens Orbitor Nuclear Camera 60 Hz for the DMSA scan.RESULTS:
The 10 DMSA false-negative patients were mostly males (80%) and infants (80%). They had fever for a mean of 1.1-day duration before admission and showed increase in acute reactants leukocyte, erythrocyte sedimentation rate, and C-reactive protein. The CT findings of renal lesions were focal in 6 (60%) cases and diffuse in 4 (40%) cases, and most of the lesions were unilateral in 80% of patients. CT proved that 22 renal lesions were neglected by DMSA. Differential renal function test by DMSA was also of no use in the evaluation of renal lesions.CONCLUSION:
In this study, DMSA scan showed limitation in finding renal cortical lesions of CT-proven APN patients. DMSA false-negative results seem to occur at early-phase disease of infantile age, but more prospective studies are needed to determine the reasons and their prevalence.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pyélonéphrite
/
Sédimentation du sang
/
Protéine C-réactive
/
Caméras à rayons gamma
/
Prévalence
/
Succimer
/
Succimer de technétium (99mTc)
/
Fièvre
/
Abdomen aigu
/
Leucocytes
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude de prévalence
/
Étude pronostique
Limites du sujet:
Enfant
/
Humains
/
Bébé
/
Mâle
langue:
Coréen
Texte intégral:
Korean Journal of Pediatrics
Année:
2010
Type:
Article
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