Successful treatment by exchange transfusion of a young infant with sodium nitroprusside poisoning / 소아과
Korean Journal of Pediatrics
;
: 805-808, 2010.
Article
Dans Anglais
| WPRIM
| ID: wpr-155472
ABSTRACT
Although sodium nitroprusside (SNP) is often used in pediatric intensive care units, cyanide toxicity can occur after SNP treatment. To treat SNP-induced cyanide poisoning, antidotes such as amyl nitrite, sodium nitrite, sodium thiosulfate, and hydroxycobalamin should be administered immediately after diagnosis. Here, we report the first case of a very young infant whose SNP-induced cyanide poisoning was successfully treated by exchange transfusion. The success of this alternative method may be related to the fact that exchange transfusion not only removes the cyanide from the blood but also activates detoxification systems by supplying sulfur-rich plasma. Moreover, exchange transfusion replaces cyanide-contaminated erythrocytes with fresh erythrocytes, thereby improving the blood's oxygen carrying capacity more rapidly than antidote therapy. Therefore, we believe that exchange transfusion might be an effective therapeutic modality for critical cases of cyanide poisoning.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Oxygène
/
Plasma sanguin
/
Sodium
/
Nitrite de sodium
/
Thiosulfates
/
Nitrite d'amyle
/
Nitroprussiate
/
Unités de soins intensifs pédiatriques
/
Ressources naturelles
/
Cyanures
Limites du sujet:
Humains
/
Bébé
langue:
Anglais
Texte intégral:
Korean Journal of Pediatrics
Année:
2010
Type:
Article
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