Mosaic Turner syndrome associated with schizophrenia
Annals of Pediatric Endocrinology & Metabolism
;
: 42-44, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-158570
ABSTRACT
Turner syndrome is a sex-chromosome disorder; occurring in 1 in 2,500 female births. There are sporadic few case reports of concomitant Turner syndrome with schizophrenia worldwide. Most Turner females had a 45,X monosomy, whereas the majority of comorbidity between Turner syndrome and schizophrenia had a mosaic karyotype (45,X/46,XX). We present a case of a 21-year-old woman with Turner syndrome, mosaic karyotype (45,X/46,XX), showing mental retardation, hypothyroidism, and schizophrenia. HOPA gene within Xq13 is related to mental retardation, hypothyroidism, and schizophrenia. Our case may be a potential clue which supports the hypothesis for involvement of genes on X chromosome in development of schizophrenia. Further studies including comorbid cases reports are need in order to discern the cause of schizophrenia in patients having Turner syndrome.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Schizophrénie
/
Syndrome de Turner
/
Chromosome X
/
Comorbidité
/
Parturition
/
Caryotype
/
Hypothyroïdie
/
Déficience intellectuelle
/
Monosomie
/
Mosaïcisme
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Annals of Pediatric Endocrinology & Metabolism
Année:
2014
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS