A case of advanced thymic carcinoma that was resected after concurrent chemoradiotherapy / 대한내과학회지
Korean Journal of Medicine
; : 645-649, 2010.
Article
de Ko
| WPRIM
| ID: wpr-162417
Bibliothèque responsable:
WPRO
ABSTRACT
Thymic carcinoma is a rare, but aggressive, tumor that often metastasizes to regional lymph nodes and distant sites and often has a poor prognosis. Although the efficacy of induction therapy in thymic carcinoma is unclear, we report the clinical course of a patient who underwent complete surgical resection after effective induction chemoradiotherapy. A 66-year-old man was diagnosed with a poorly differentiated thymic carcinoma (Masaoka stage III). The tumor was considered unresectable due to sternal invasion and surrounding fat infiltration. Two cycles of chemotherapy, consisting of paclitaxel (180 mg/m2 on D1) and cisplatin (80 mg/m2 on D1) combined with mediastinal radiotherapy (total 50 Gy) were performed concurrently; the mass decreased to a resectable size. Subsequently, he received adjuvant chemotherapy and adjuvant radiation therapy. He is currently alive and ambulatory and has remained disease-free for 19 months. This case demonstrates that induction chemoradiotherapy with paclitaxel and cisplatin may be tolerated and useful for patients with locally advanced thymic carcinoma.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Pronostic
/
Thymome
/
Cisplatine
/
Traitement médicamenteux adjuvant
/
Paclitaxel
/
Chimioradiothérapie
/
Noeuds lymphatiques
Type d'étude:
Prognostic_studies
Limites du sujet:
Aged
/
Humans
langue:
Ko
Texte intégral:
Korean Journal of Medicine
Année:
2010
Type:
Article