Cost-utility analysis of treatments for stage IB cervical cancer / 부인종양
Journal of Gynecologic Oncology
;
: 97-104, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-16243
ABSTRACT
OBJECTIVE:
To analyze the cost-utility of two common clinical practices for stage IB cervical cancer patients from provider and societal viewpoints.METHODS:
A decision tree model was conducted to examine value for expenditure between the following (1) radical hysterectomy with pelvic lymph node dissection (RHPLND) with or without postoperative adjuvant therapy according to the risk of recurrence and (2) concurrent chemoradiotherapy (CCRT). The relevant studies were identified to extract the probability data, and meta-analysis was performed. Direct medical costs were estimated from hospital database and medical records review. Direct non-medical costs and utility parameters were obtained through interviews with patients to estimate quality-adjusted life years (QALYs) outcome. The time horizon was according to the life expectancy of Thai women.RESULTS:
From provider viewpoint, RHPLND and CCRT resulted in approximate costs of US $5,281 and US $5,218, respectively. The corresponding costs from societal viewpoint were US $6,533 and US $6,335, respectively. QALYs were 16.40 years for RHPLND and 15.94 years for CCRT. The estimated incremental cost effectiveness ratio of RHPLND in comparison to CCRT from provider and societal viewpoints were US $100/QALY and US $430/QALY, respectively. RHPLND had more cost-effectiveness than CCRT if patients did not need adjuvant therapy. The most effective parameter in model was a direct medical cost of CCRT. At the current ceiling ratio in Thailand, RHPLND provides better value for money than CCRT, with a probability of 75%.CONCLUSION:
RHPLND is an efficient treatment for stage IB cervical cancer. This advantage is only for patients who require no adjuvant treatment.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Récidive
/
Thaïlande
/
Arbres de décision
/
Tumeurs du col de l'utérus
/
Dossiers médicaux
/
Espérance de vie
/
Analyse coût-bénéfice
/
Dépenses de santé
/
Années de vie ajustées sur la qualité
/
Asiatiques
Type d'étude:
Évaluation en économique de la santé
/
Étude pronostique
Limites du sujet:
Femelle
/
Humains
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Journal of Gynecologic Oncology
Année:
2014
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS