Acute oxalate nephropathy caused by ethylene glycol poisoning
Kidney Research and Clinical Practice
;
: 249-252, 2012.
Article
Dans Anglais
| WPRIM
| ID: wpr-165350
ABSTRACT
Ethylene glycol (EG) is a sweet-tasting, odorless organic solvent found in many agents, such as anti-freeze. EG is composed of four organic acids glycoaldehyde, glycolic acid, glyoxylic acid and oxalic acid in vivo. These metabolites are cellular toxins that can cause cardio-pulmonary failure, life-threatening metabolic acidosis, central nervous system depression, and kidney injury. Oxalic acid is the end product of EG, which can precipitate to crystals of calcium oxalate monohydrate in the tubular lumen and has been linked to acute kidney injury. We report a case of EG-induced oxalate nephropathy, with the diagnosis confirmed by kidney biopsy, which showed acute tubular injury of the kidneys with extensive intracellular and intraluminal calcium oxalate monohydrate crystal depositions.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Acidose
/
Biopsie
/
Oxalate de calcium
/
Système nerveux central
/
Éthylène glycol
/
Acide oxalique
/
Dépression
/
Éthylènes
/
Atteinte rénale aigüe
/
Glycolates
langue:
Anglais
Texte intégral:
Kidney Research and Clinical Practice
Année:
2012
Type:
Article
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