Animal Experiments of Heart Transplantation for Complicated Congenital Heart Disease in Neonate / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 504-509, 1999.
Article
Dans Coréen
| WPRIM
| ID: wpr-166158
ABSTRACT
BACKGROUND:
Heart transplantation is considerated for a selected certain group of complicated congenital heart disease in neonates because corrective surgery is very difficult and has high mortality. Precise planning of transplantation is necessary to adequately fit the donor heart to the recipient. MATERIAL ANDMETHOD:
We have performed 4 neonatal pig heart transplantations to test the technical feasibility. Experiment 1 The transplantation was performed using the same technique as the adult heart transplantation. Experiment 2 The transplantation for hypoplastic left heart syndrome was simulated as we reconstructed the whole aortic arch with donor aorta. Experiment 3 The heart transplantation was done with radical pulmonary artery reconstruction. Experiment 4 The experiment was performed for a long term survival.RESULT:
Preoperative planning was very important for adequate fitting. All animals could be weaned from cardiopulmonary bypass, however, two animals died due to bleeding at pulmonary artery and left atrium.CONCLUSION:
We concluded that the neonatal heart transplantation can be applied in some complicated Further using animal model is mandatory.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Aorte
/
Aorte thoracique
/
Artère pulmonaire
/
Donneurs de tissus
/
Pontage cardiopulmonaire
/
Mortalité
/
Transplantation cardiaque
/
Hypoplasie du coeur gauche
/
Modèles animaux
/
Expérimentation animale
Type d'étude:
Étude pronostique
Limites du sujet:
Animaux
/
Humains
langue:
Coréen
Texte intégral:
The Korean Journal of Thoracic and Cardiovascular Surgery
Année:
1999
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS