Topical Autologous Fibronectin in the Treatment of Persistent Corneal Epithelial defects
Journal of the Korean Ophthalmological Society
;
: 29-36, 1989.
Article
Dans Coréen
| WPRIM
| ID: wpr-167094
ABSTRACT
Fibronectin, a glycoprotein, is present in plasma and extracellular matrix and is responsible for cellular adhesion. Fibronectin was purified from autologous plasma of two persistent corneal epithelial defect patients by affinity chromatogaphy and administered topically 500 micro ml, 2 dropsper time, five times a day for 3 weeks. Reepithelization began three to seven days after initiation of treatment with autologous purified fibronectin eyedrops, and epithelial defects healed nearly completely and subjective symptoms were relieved. No side effects were observed. Over a follow-up period of 4 to 23 wks, no recurrences were noted.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Solutions ophtalmiques
/
Plasma sanguin
/
Récidive
/
Glycoprotéines
/
Études de suivi
/
Fibronectines
/
Matrice extracellulaire
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Ophthalmological Society
Année:
1989
Type:
Article
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