Your browser doesn't support javascript.
loading
A case of familial primary pulmonary hypertension / 대한내과학회지
Korean Journal of Medicine ; : 313-317, 2006.
Article de Ko | WPRIM | ID: wpr-17055
Bibliothèque responsable: WPRO
ABSTRACT
Primary Pulmonary Hypertension (PPH) predominantly affects women frequently in the prime of life and usually leads to death from right ventricular failure within a few years after diagnosis. The prevalence and etiology of familial PPH are uncertain. The age of onset is variable and penetrance is incomplete. Although its occurrence in families was reported within a few years after the original clinical report, PPH was formely believed rarely to have a gene basis. Recent progress has not only clarified a basic molecular mechanism for PPH in familise, but also identified mutations of the same gene in many sporadic PPH patients, suggestion that its basis is commonly genetic. We report a case of familial PPH in a 20-year-old male with exetional dyspnea, who has a family history of PPH in his mother. We report this case with a brief review of recent literatures.
Sujet(s)
Mots clés
Texte intégral: 1 Indice: WPRIM Sujet Principal: Prévalence / Gènes vif / Âge de début / Pénétrance / Diagnostic / Dyspnée / Hypertension pulmonaire / Mères Type d'étude: Diagnostic_studies / Prevalence_studies / Prognostic_studies Limites du sujet: Female / Humans / Male langue: Ko Texte intégral: Korean Journal of Medicine Année: 2006 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Prévalence / Gènes vif / Âge de début / Pénétrance / Diagnostic / Dyspnée / Hypertension pulmonaire / Mères Type d'étude: Diagnostic_studies / Prevalence_studies / Prognostic_studies Limites du sujet: Female / Humans / Male langue: Ko Texte intégral: Korean Journal of Medicine Année: 2006 Type: Article