The Predictable Factors for the Mortality of Fatal Asthma with Acute Respiratory Failure / 결핵

ABSTRACT

BACKGROUNDS Previous reports have revealed a high morbidity and mortality in fatal asthma patients, especially those treated in the medical intensive care unit(MICU). But it has not been well known about the predictable factors for the mortality of fatal asthma(FA) with acute respiratory failure. In order to define the predictable factors for the mortality of FA at the admission to MICU, we analyzed the relationship between the clinical parameters and the prognosis of FA patients. METHODS: A retrospective analysis of all medical records of 59 patients who had admitted for FA to MICU at a tertiary care MICU from January 1992 to March 1997 was performed. RESULTS: Over all mortality rate was 32.2% and 43 patients were mechanically ventilated. In uni-variate analysis, the death group had significantly older age (66.2 +/- 10.5 vs. 51.0 +/- 18.8 year), lower FVC(59.2 +/- 21.1 vs. 77.6 +/- 23.3%) and lower FEV1(41.4 +/- 18.8 vs. 61.1 +/- 23.30%), and longer total ventilation time (255.0 +/- 236.3 vs. 98.1 +/- 120.4 hour)(por=40) and PaO2/FiO2 ratio (<200) on the second day of MICU, which might reflect the response of treatment, rather than initially presented clinical parameters would be more important predictable factors of mortality in patients with FA.