A Case of Sarcoidosis That Improved upon Discontinuation of Etanercept
Journal of Rheumatic Diseases
;
: 187-192, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-173096
ABSTRACT
A 31-year-old man who had been prescribed etanercept over a 3-year period for treatment of ankylosing spondylitis presented with newly developed dry cough, chills, myalgia, and weight loss. Chest computed tomography showed multiple reticulonodular pulmonary infiltrates and bilateral mediastinal, hilar, and peribronchial lymphadenopathy. Biopsy of a paratracheal lymph node revealed chronic granulomatous inflammation without necrosis, and the serum angiotensin-converting enzyme level was elevated. Sarcoidosis was diagnosed. His laboratory and radiological findings, and clinical symptoms improved only after discontinuation of etanercept without treatment. Although etanercept-induced sarcoidosis is rare, this case report suggests that sarcoidosis should be considered in the differential diagnosis of patients treated with the tumor necrosis factor inhibitor.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Sarcoïdose
/
Pelvispondylite rhumatismale
/
Thorax
/
Biopsie
/
Perte de poids
/
Facteur de nécrose tumorale alpha
/
Toux
/
Sensation de froid
/
Diagnostic différentiel
/
Myalgie
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Humains
langue:
Anglais
Texte intégral:
Journal of Rheumatic Diseases
Année:
2016
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS