Intravenous albumin for the prevention of contrast-induced nephropathy in patients with liver cirrhosis and chronic kidney disease undergoing contrast-enhanced CT
Kidney Research and Clinical Practice
;
: 106-111, 2012.
Article
Dans Anglais
| WPRIM
| ID: wpr-174799
ABSTRACT
BACKGROUND:
The purpose of this study was to evaluate the incidence of contrast-induced nephropathy (CIN), and the effect of intravenous albumin for prophylaxis of CIN in patients with liver cirrhosis (LC) and chronic kidney disease (CKD).METHODS:
We conducted a retrospective study of 81 subjects with LC and CKD (estimated glomerular filtration rate (eGFR) or =25% or > or =0.5mg/dL in serum creatinine level.RESULTS:
Overall, CIN developed in three patients (3.7%). Of the 81 subjects, 43 received sodium bicarbonate solution and 38 received albumin. Both groups were comparable with regard to age, sex, diabetes mellitus, and baseline eGFR. The albumin group showed a significantly poorer liver function profile. CIN incidence did not differ significantly between the groups it occurred in one (2.3%) of the 43 subjects receiving sodium bicarbonate and two (5.3%) of the 38 subjects receiving albumin (P=0.6). However, the albumin group showed a significantly smaller increase in body weight (P=0.03).CONCLUSION:
The incidence of CIN in patients with LC and CKD undergoing contrast-enhanced CT after preventive measures was relatively low. The incidence of CIN was not significantly different between sodium bicarbonate and albumin groups.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Poids
/
Incidence
/
Études rétrospectives
/
Hydrogénocarbonate de sodium
/
Créatinine
/
Diabète
/
Insuffisance rénale chronique
/
Débit de filtration glomérulaire
/
Foie
/
Cirrhose du foie
Type d'étude:
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Kidney Research and Clinical Practice
Année:
2012
Type:
Article
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