Is There an Association Between Serum Prostate-Specific Antigen Values and Serum Testosterone Levels in Healthy Men?
Korean Journal of Urology
;
: 465-469, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-178074
ABSTRACT
PURPOSE:
To evaluate the relationship between levels of total testosterone and total prostate-specific antigen (PSA) in healthy men with PSA or =50 years.RESULTS:
In all patients, the mean values for serum PSA and total testosterone were 1.27+/-0.88 ng/mL and 404.04+/-158.86 ng/mL, respectively. No correlation was detected between serum PSA and testosterone levels in either subgroup (group I, r=0.072, p=0.363; group II, r=0.031, p=0.900) or in patients aged or =50 years and in patients aged <50 years were 417.01+/-163.35 and 344.16+/-120.21 ng/dL, respectively (p=0.02).CONCLUSIONS:
No impact of testosterone was found on the PSA level in healthy men with PSA <4 ng/mL. Therefore, a high serum testosterone level may not mandate adjustment of PSA values. This serum sex hormone showed a significant increment after the age of 50 years. Further studies including a larger number of patients should be carried out to confirm these findings.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Valeurs de référence
/
Testostérone
/
Vieillissement
/
Kallicréines
/
Marqueurs biologiques tumoraux
/
Antigène spécifique de la prostate
Limites du sujet:
Adulte très âgé
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Korean Journal of Urology
Année:
2014
Type:
Article
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