HRCT Findings of Bleomycin-Related Lung Toxicity: A Report of 2 Case
Journal of the Korean Radiological Society
;
: 83-86, 1997.
Article
Dans Anglais
| WPRIM
| ID: wpr-17851
ABSTRACT
Many drugs can result in a variety of pathologic reactions in the lung, especially the cytotoxic drugs. Amongcytotoxic drugs bleomycin is a prototype. Bleomycin-related pulmonary toxicity is usually known as dose-dependent and can be enhanced with concurrent oxygen therapy, irradiation, or other chemotherapeutic agents. The incidence of bleomycin-induced pulmonary toxicity has been reported as varying from 2 to 46%, and 1% of fatal lung disease. We describe the radiographic and HRCT findings of bleomycin-related pulmonary toxicity developed in two patients one in ovarian teratocarcinoma, the other malignant lymphoma patient. Chest radiographs and HRCT of these patients showed ground-glass opacities, consolidation, linear and reticular opacities, and interlobular septal thickening. These abnormalities were bilateral, and symmetrical and were found predominantly in the area of mid-and lower-lung zone.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Oxygène
/
Bléomycine
/
Radiographie thoracique
/
Incidence
/
Tératocarcinome
/
Poumon
/
Maladies pulmonaires
/
Lymphomes
Type d'étude:
Etude diagnostique
/
Etude d'incidence
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Journal of the Korean Radiological Society
Année:
1997
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS