The comparison of monitored anesthesia care with dexmedetomidine and spinal anesthesia during varicose vein surgery
Annals of Surgical Treatment and Research
; : 245-252, 2014.
Article
de En
| WPRIM
| ID: wpr-17869
Bibliothèque responsable:
WPRO
ABSTRACT
PURPOSE: The purpose of this study was to investigate the effectiveness and safety of monitored anesthesia care (MAC) using dexmedetomidine for its sedative and analgesic effect during varicose vein surgery. METHODS: Forty-two patients, who underwent varicose vein surgery, were divided into the MAC group (n = 20) or the spinal anesthesia group (n = 22) for randomized clinical trial. In the MAC group, dexmedetomidine was administered by a loading dose of 1 microg/kg for 10 minutes, followed by a maintenance infusion of 0.2-1.0 microg/kg/hr. Ketamine was used for intermittent injection. In the spinal anesthesia group, midazolam was used for sedation. Intraoperative vital signs, the number of adverse events, and the satisfaction of patients and surgeons concerning the anesthetic condition were compared between the two groups. RESULTS: Systolic blood pressure was intraoperatively significantly different over time between the two groups. The groups had statistical differences in the change in heart rate with regard to time. In the postanesthetic care unit, patients and surgeons in the MAC group had a lower satisfaction score, compared to patients and surgeons in the spinal anesthesia group. However, in the recovery period, patients had a positive perception concerning MAC anesthesia. In addition, without significant adverse events, the MAC group had a shorter time to possible ambulation, which indicated an early recovery. CONCLUSION: We believe that MAC using dexmedetomidine in combination with ketamine may be an alternative anesthetic technique for varicose vein surgery with regard to a patient's preference and medical condition.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Varices
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Pression sanguine
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Midazolam
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Marche à pied
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Dexmédétomidine
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Signes vitaux
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Rythme cardiaque
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Anesthésie
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Kétamine
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Rachianesthésie
Type d'étude:
Clinical_trials
Limites du sujet:
Humans
langue:
En
Texte intégral:
Annals of Surgical Treatment and Research
Année:
2014
Type:
Article