Treatment outcome of ductal carcinoma in situ patients treated with postoperative radiation therapy
Radiation Oncology Journal
;
: 1-6, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-178913
ABSTRACT
PURPOSE:
To evaluate the outcome of ductal carcinoma in situ (DCIS) patients who underwent surgery followed by radiation therapy (RT). MATERIALS ANDMETHODS:
We retrospectively reviewed 106 DCIS patients who underwent surgery followed by postoperative RT between 1994 and 2006. Ninety-four patients underwent breast-conserving surgery, and mastectomy was performed in 12 patients due to extensive DCIS. Postoperative RT was delivered to whole breast with 50.4 Gy/28 fx. Tumor bed boost was offered to 7 patients (6.6%). Patients with hormonal receptor-positive tumors were treated with hormonal therapy.RESULTS:
The median follow-up duration was 83.4 months (range, 33.4 to 191.5 months) and the median age was 47.8 years. Ten patients (9.4%) had resection margin or =1 mm) was the significant prognostic factor for IBTR in univariate and multivariate analyses (p < 0.001 and p = 0.016, respectively).CONCLUSION:
Postoperative RT for DCIS can achieve favorable treatment outcome. Resection margin was the important prognostic factor for IBTR in the DCIS patients who underwent postoperative RT.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Récidive
/
Région mammaire
/
Tumeurs du sein
/
Mastectomie partielle
/
Analyse multifactorielle
/
Taux de survie
/
Études rétrospectives
/
Études de suivi
/
Résultat thérapeutique
/
Carcinome intracanalaire non infiltrant
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Radiation Oncology Journal
Année:
2014
Type:
Article
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