The Clinical Effect of 5% Imiquimod Cream in the Treatment of Verruca Plana / 대한피부과학회지
Korean Journal of Dermatology
; : 1-5, 2005.
Article
Dans Ko
| WPRIM
| ID: wpr-179691
Responsable en Bibliothèque :
WPRO
ABSTRACT
BACKGROUND: Despite numerous therapeutic options, the treatment of verruca plana remains unsatisfactory for both patients and physicians. Imiquimod, a novel topical immune response modifier, has been successfully used for the treatment of external anogenital warts. OBJECTIVE: The purpose of this study was to investigate the efficacy of imiquimod in treatment of verruca plana. METHOD: Fifteen patients with verruca plana were treated with 5% imiquimod cream that was self-applied 3 times a week and left in place overnight. Assessment for responses and side effects was performed every 2 weeks until clinical cure or up to 12 weeks. RESULTS: 10 of 15 (66.7%) patients achieved a excellent result (>75% improvement), and 11 (73%) patients achieved a good result (>50% improvement). With regard to the location of the lesions, 10 of 12 (83%) patients with lesions on the face and neck achieved a clear result (>95% improvement), but only 2 of 7 (28%) patients with lesions on the extremities achieved a clear result. Local inflammatory reactions were the most common adverse events, however, they were generally mild and transient. CONCLUSION: 5% imiquimod cream, applied by the patient, is an effective treatment modality for verruca plana.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Verrues
/
Membres
/
Cou
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Korean Journal of Dermatology
Année:
2005
Type:
Article