Dose Dependent Effects of Intravitreal Triamcinolone Acetonide on Diffuse Diabetic Macular Edema
Korean Journal of Ophthalmology
;
: 80-85, 2009.
Article
Dans Anglais
| WPRIM
| ID: wpr-180448
ABSTRACT
PURPOSE:
To evaluate the effect of different doses of intravitreal triamcinolone acetonide on diffuse diabetic macular edema.METHODS:
In a retrospective study, 44 eyes with diffuse diabetic macular edema were treated with an intravitreal injection of 4 mg (n=12 eyes), 8 mg (n=17) or 25 mg (n=15) of triamcinolone acetonide (TA). Optical coherence tomography, best-corrected logMAR visual acuity and Goldmann tonometry were performed at baseline, 1 week, and 1, 3, 6, 9 and 12 months after treatment. Mean follow-up was 9.8 months (standard deviation=2.3) with a range of 5-12 months.RESULTS:
The duration of intravitreal TA effects on macular thickness and visual acuity increased with increasing dosage. An observed increase in intraocular pressure induced by TA was not significantly associated with dosage.CONCLUSIONS:
In patients with diffuse diabetic macular edema who receive intravitreal TA, effects may last longer after a dosage of 25 mg, than after lower doses of 8 mg or 4 mg.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Facteurs temps
/
Corps vitré
/
Triamcinolone acétonide
/
Acuité visuelle
/
Oedème maculaire
/
Études rétrospectives
/
Études de suivi
/
Résultat thérapeutique
/
Tomographie par cohérence optique
/
Rétinopathie diabétique
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Adulte
/
Adulte très âgé
/
Aged80
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Korean Journal of Ophthalmology
Année:
2009
Type:
Article
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