In Vitro Effects of Some Herbs Used in Egyptian Traditional Medicine on Viability of Protoscolices of Hydatid Cysts
The Korean Journal of Parasitology
; : 255-263, 2011.
Article
de En
| WPRIM
| ID: wpr-182108
Bibliothèque responsable:
WPRO
ABSTRACT
The present work evaluated the effects of alcoholic extracts of salvia (Salvia officinalis), thyme (Thymus vulgaris), and 2 pure compounds (thymol and menthol) on the viability of Echinococcus granulosus protoscolices in vitro. Four different concentrations of each extract (2,500, 1,500, 1,000, and 500 microg/ml) and 3 different concentrations each of thymol and menthol (50, 10, and 1 microg/ml) were used. Concentration of 2,500 microg/ml of both extracts showed a significant protoscolicidal activity on the 6th day. Complete loss of viability of protoscolices occurred with 500 microg/ml concentration of both extracts at day 6 and day 7 post-treatment (PT), respectively. Pure compounds, i.e., menthol and thymol, showed potent effects with 50 microg/ml concentration at day 2 and day 5 PT, respectively. These effects were compared with those of albendazole sulfoxide (800 microg/ml), a commonly used treatment drug for hydatidosis. Krebs-Ringer solution and the hydatid cystic fluid at a ratio of 4:1 was a good preservative solution which kept the protoscolices viable for 15 days.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Plantes médicinales
/
Facteurs temps
/
Chameaux
/
Extraits de plantes
/
Survie cellulaire
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Salvia officinalis
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Echinococcus granulosus
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Thymus (plante)
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Échinococcose pulmonaire
/
Poumon
Limites du sujet:
Animals
langue:
En
Texte intégral:
The Korean Journal of Parasitology
Année:
2011
Type:
Article