Pathogenesis and Treatment of Intestinal Behcet's Disease / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 3-8, 2007.
Article
Dans Coréen
| WPRIM
| ID: wpr-182232
ABSTRACT
Intestinal Behcet's disease (BD) refers to colonic ulcerative lesions documented by objective measures in patients with BD. Although the causes of intestinal BD are unknown, genetic, environmental, and immunological factors have been suggested. Intestinal BD is common in BD patients from Far East, while it is uncommon in those from the Middle East. The reasons for such peculiar geographic distribution in intestinal BD are unknown, but may provide clues for the elucidation of putative etiological agents or genetic factors that might be associated with intestinal BD. Although the treatment of Crohn's disease has improved significantly during past decade, the treatment of intestinal BD is still problematic. Corticosteroids, sulfasalazine, immunomodulators, and colchicines have been used to treat intestinal BD with varying degree of success. Thalidomide and its analogues also appear to be applicable. Monoclonal antibodies to TNF-alpha have recently been focused as a novel therapeutic option for patients with intestinal BD.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Sulfasalazine
/
Thalidomide
/
Rectocolite hémorragique
/
Maladie de Crohn
/
Colchicine
/
Maladie de Behçet
/
Facteur de nécrose tumorale alpha
/
Hormones corticosurrénaliennes
/
Facteurs immunologiques
Type d'étude:
Etude d'étiologie
/
Étude pronostique
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
The Korean Journal of Gastroenterology
Année:
2007
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS