The Effect of Dilution with 0.9% Normal Saline on Reducing Withdrawal Movement Induced by Rocuronium Injection
Anesthesia and Pain Medicine
;
: 26-29, 2007.
Article
Dans Coréen
| WPRIM
| ID: wpr-182662
ABSTRACT
BACKGROUND:
The intravenous injection of rocuronium after loss of consciousness during induction of general anesthesia can cause a withdrawal movement of hand, arm or more than one extremity. We designed this study to examine diluted rocuronium (2 mg/ml) with 0.9% normal saline can reduce withdrawal movement.METHODS:
Eighty healthy female patients (aged 19-63) scheduled for general anesthesia were randomly assigned to one of two groups; Group 1 (rocuronium 10 mg/ml) and Group 2 (rocuronium diluted to 2 mg/ml with 0.9% normal saline). After loss of consciousness and eyelid reflex by intravenous injection of thiopental sodium 5 mg/kg, rocuronium (0.6 mg/kg) was injected at the speed of 1 ml/sec in both groups. The incidence and severity of withdrawal movements were assessed by using four-point scales.RESULTS:
The incidence and severity of withdrawal movement in response to rocuronium injection were significantly reduced in Group 2 compared to Group 1 (P < 0.05).CONCLUSIONS:
Dilution of rocuronium 10 mg/ml to 2 mg/ml with 0.9% normal saline was significantly effective for reducing withdrawal movement during induction of general anesthesia. This is a simple and effective strategy for preventing rocuronium-induced withdrawal movement.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Bras
/
Réflexe
/
Thiopental
/
Perte de conscience
/
Poids et mesures
/
Incidence
/
Membres
/
Paupières
/
Main
/
Injections veineuses
Type d'étude:
Etude d'incidence
/
Étude pronostique
Limites du sujet:
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Anesthesia and Pain Medicine
Année:
2007
Type:
Article
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