A Case of Pancreatic Panniculitis / 대한피부과학회지

ABSTRACT

Pancreatic panniculitis is a subcutaneous fat necrosis associated with pancreatic disease. We report a case of pancreatic panniculitis associated with chronic pancreatitis. The patient was a 47-year-old man who was a severe alcoholic. He was diagnosed with chronic pancreatitis and inferior vena cava thrombosis 2 months before. He presented with multiple, tender, erythematous, subcutaneous nodules on both lower legs, and also had pitting edema with tenderness on the left ankle. Laboratory examination showed an increase in serum blood amylase and lipase. Histopathologic findings showed subcutaneous focal fat necrosis, dense neutrophil infiltration and anucleated "ghost cells". Stippled basophilic material was deposited in and around the necrotic subcutaneous fat tissue. The lesions subsided gradually with improvement of the chronic pancreatitis.