Flecainide-Induced Torsade de Pointes Successfully Treated with Intensive Pharmacological Therapy
International Journal of Arrhythmia
;
: 97-102, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-186466
ABSTRACT
Flecainide acetate is a potent class IC anti-arrhythmic drug with a major sodium channel blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse. It may also result in life-threatening arrhythmia, although cases of flecainide-induced torsades de pointes are rare. Furthermore, the electrical and hemodynamic deteriorations observed during flecainide toxicity may not respond to conventional treatments. In the present study, we report the case of a 20-year-old Korean man with flecainide poisoning, who presented with hypotension. The patient was successfully treated with sodium bicarbonate, amiodarone, MgSO₄, and lidocaine, with no recourse to extracorporeal therapy. Although there is no standard therapy for flecainide toxicity, this report demonstrates that intensive pharmacological treatment is beneficial in cases of flecainide overdose.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Intoxication
/
Troubles du rythme cardiaque
/
Choc
/
Canaux sodiques
/
Torsades de pointes
/
Flécaïnide
/
Hydrogénocarbonate de sodium
/
Effets secondaires indésirables des médicaments
/
Amiodarone
/
Hémodynamique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
International Journal of Arrhythmia
Année:
2016
Type:
Article
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