Cytomegalovirus Ventriculoencephalitis after Unrelated Double Cord Blood Stem Cell Transplantation with an Alemtuzumab-containing Preparative Regimen for Philadelphia-positive Acute Lymphoblastic Leukemia
Journal of Korean Medical Science
;
: 630-633, 2010.
Article
Dans Anglais
| WPRIM
| ID: wpr-188010
ABSTRACT
Despite the prophylaxis and preemptive strategies using potent antiviral agents, cytomegalovirus (CMV) remains a major infectious cause of morbidity and mortality in allogeneic stem cell transplantation (SCT) recipients. Delayed immune reconstitution after SCT, such as cord blood and T-cell depleted SCT with the use of alemtuzumab, has been associated with an increased frequency of CMV disease as well as CMV reactivation. CMV disease involving central nervous system is an unusual presentation in the setting of SCT. We report a case of CMV ventriculoencephalitis after unrelated double cord blood SCT with an alemtuzumab-containing preparative regimen for Philadelphia-positive acute lymphoblastic leukemia.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Issue fatale
/
Infections à cytomégalovirus
/
Conditionnement pour greffe
/
Cytomegalovirus
/
Transplantation de cellules souches de sang du cordon
/
Encéphalite
/
Leucémie-lymphome lymphoblastique à précurseurs B et T
/
Anticorps monoclonaux humanisés
/
Anticorps monoclonaux
/
Anticorps antitumoraux
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Journal of Korean Medical Science
Année:
2010
Type:
Article
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