Cellular signaling in tissue regeneration
Yonsei Medical Journal
;
: 692-703, 2000.
Article
Dans Anglais
| WPRIM
| ID: wpr-189808
ABSTRACT
With recent progress in stem cell-based research, there has been tremendous interest in stem cell-based tissue regeneration. Stem cells can be differentiated into specialized cells/tissues by growth factors and cytokines. These small molecules are thought to play an important role in both wound healing and tissue regeneration. However, their biological activity and signal transduction during tissue regeneration are poorly understood. With recent advances in signal transduction by growth factors, the receptor kinases and G protein-coupled receptors, an understanding in the underlying mechanism of how these factors regulate tissue regeneration beginning to take place. In this review, the potential underlying mechanisms of growth factor signaling in normal tissue regeneration and chronic wound healing is discussed. Thus, it is an aim to provide a basis for designing more specific therapies for tissue regeneration in the near future.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Régénération
/
Cicatrisation de plaie
/
Transduction du signal
/
Phénomènes physiologiques cellulaires
/
Maladie chronique
/
Substances de croissance
/
Chimiokines
/
Chéloïde
/
Animaux
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Yonsei Medical Journal
Année:
2000
Type:
Article
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